Opportunity Information: Apply for PAR 23 022

The Javits Neuroscience Investigator Award Extension Request (PAR-23-022) is a National Institutes of Health grant opportunity administered by the National Institute of Neurological Disorders and Stroke (NINDS). It supports a very specific purpose: it allows investigators who already hold an active NINDS Javits Neuroscience Investigator Award (an R37) to apply for the second segment of that award, extending their support beyond the initial period. The Javits program is designed for investigators with an established record of exceptional scientific accomplishment and unusually high research productivity, and it is structured to provide longer-term stability than a typical research project award.

The core goal of the Javits R37 mechanism is to provide up to seven total years of funding split into two phases. The first phase can last up to four years, and the second phase can add up to three additional years. This particular announcement is only about that second phase. In other words, it is not a general competition for new Javits awards, and it is not meant for investigators who are not already current NINDS Javits recipients. It is essentially an extension request pathway that enables eligible awardees to continue their research program with sustained support, assuming they meet NINDS expectations for continued outstanding performance and progress.

A notable administrative note embedded in the announcement states that NIH Institutes and Centers (ICs) should not join this opportunity and that the relevant submission route is a "Type 4" action intended specifically for NS (NINDS) R37 applications. The listing also indicates "Clinical Trial Optional," meaning the proposed work may include a clinical trial but does not have to; the key point is that the application must fit within the scope and requirements of the NINDS R37 Javits extension request framework.

Eligibility in the posting is presented broadly, reflecting the standard range of organizational applicants that NIH can fund, such as public and private institutions of higher education, nonprofit and for-profit entities (excluding small business restrictions in this listing), small businesses, and various levels of government. The announcement also explicitly names a wide range of institution types that may apply when otherwise eligible, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities, Tribally Controlled Colleges and Universities, tribal governments and organizations (including those other than federally recognized), faith-based and community-based organizations, U.S. territories and possessions, and even non-U.S. (foreign) entities and regional organizations. Practically, though, the controlling constraint is not the organizational category; it is the requirement that the applicant be a currently funded NINDS Javits (R37) recipient seeking the second phase of the same award.

From a classification standpoint, this is a discretionary grant opportunity in the health funding activity category, associated with CFDA number 93.853. The original closing date listed is 2025-09-15, and the opportunity was created on 2022-08-15. The award ceiling and expected number of awards are not specified in the provided source data, which is common for continuation/extension-style announcements where funding levels depend heavily on the existing award structure, institute budgets, and the specifics of the requested extension.

Overall, this opportunity functions as a continuation gateway for a select group of high-performing NINDS-supported investigators, offering the possibility of up to three more years of funding to maintain momentum, pursue longer-range scientific goals, and build on the productivity that originally justified the Javits designation.

  • The National Institutes of Health in the health sector is offering a public funding opportunity titled "Javits Neuroscience Investigator Award Extension Request (Type 4 Clinical Trial Optional)" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.853.
  • This funding opportunity was created on 2022-08-15.
  • Applicants must submit their applications by 2025-09-15. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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FAQs: Javits Neuroscience Investigator Award Extension Request (PAR-23-022)

What is the Javits Neuroscience Investigator Award Extension Request (PAR-23-022)?

This is an NIH grant opportunity administered by the National Institute of Neurological Disorders and Stroke (NINDS). Its purpose is narrowly defined: it provides a way for investigators who already hold an active NINDS Javits Neuroscience Investigator Award (R37) to request the second segment (extension phase) of that same award.

Is this opportunity for new Javits (R37) awards?

No. The announcement is only about the second segment of an existing NINDS Javits R37 award. It is not a general competition to obtain a new Javits award and is not intended for investigators who are not already current NINDS Javits recipients.

Who is the intended applicant for this extension request?

The intended applicant is an investigator who currently has an active NINDS Javits Neuroscience Investigator Award (R37) and is seeking to extend support into the second phase of the award.

What does the Javits R37 funding structure look like overall?

The Javits R37 mechanism is designed to provide up to seven total years of support split into two phases: an initial phase of up to four years, followed by a second phase of up to three additional years. This funding opportunity is specifically for that second phase.

How many additional years of support can this extension provide?

Up to three additional years, as the second segment of the overall Javits R37 structure.

What is the main goal of the Javits program?

The program is designed for investigators with an established record of exceptional scientific accomplishment and unusually high research productivity. It is structured to provide longer-term stability than a typical research project award, supporting sustained progress and longer-range scientific goals.

Which NIH Institute administers this opportunity?

NINDS (the National Institute of Neurological Disorders and Stroke) administers this opportunity.

Can other NIH Institutes and Centers participate in this announcement?

The announcement includes an administrative note indicating that NIH Institutes and Centers (ICs) should not join this opportunity.

What submission/action type is associated with this extension request?

The announcement indicates the relevant submission route is a "Type 4" action intended specifically for NS (NINDS) R37 applications.

Are clinical trials allowed under this opportunity?

Yes, clinical trials are optional. The listing indicates "Clinical Trial Optional," meaning the proposed work may include a clinical trial but does not have to, as long as the application fits within the NINDS R37 Javits extension request framework.

What kinds of organizations are listed as eligible applicants?

The eligibility description is broad and reflects the range of organizational applicants NIH may fund. It includes public and private institutions of higher education, nonprofit and for-profit entities, small businesses, and various levels of government.

Does the announcement mention specific institution types that may apply?

Yes. It explicitly names many institution types, including Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions, Hispanic-serving Institutions, Historically Black Colleges and Universities (HBCUs), Tribally Controlled Colleges and Universities (TCCUs), tribal governments and organizations (including those other than federally recognized), faith-based and community-based organizations, and U.S. territories and possessions.

Are non-U.S. (foreign) entities included in the eligibility language?

Yes. The announcement explicitly includes non-U.S. (foreign) entities and regional organizations in the eligibility language, though the practical constraint remains that the applicant must be a current NINDS Javits (R37) recipient seeking the second phase of that award.

If my organization type is listed as eligible, does that mean I can apply?

Not necessarily. While many organization categories are listed, the controlling requirement described is that the applicant be a currently funded NINDS Javits (R37) recipient applying for the second segment of the same award.

What is the funding activity category for this opportunity?

The opportunity is described as a discretionary grant opportunity in the health funding activity category.

What is the CFDA number associated with this grant opportunity?

The CFDA number provided is 93.853.

What is the listed closing date for the opportunity?

The original closing date listed is 2025-09-15.

When was this opportunity created?

The opportunity was created on 2022-08-15.

Is there an award ceiling listed?

No. The award ceiling is not specified in the provided source data.

Is the expected number of awards listed?

No. The expected number of awards is not specified in the provided source data.

Why might award amounts and number of awards be unspecified for this announcement?

The provided description notes this is common for continuation/extension-style announcements, where funding levels can depend on the existing award structure, institute budgets, and the specifics of the requested extension.

What does "extension request pathway" mean in this context?

It refers to a process intended to allow eligible, already-funded NINDS Javits (R37) awardees to continue into the second phase of the award, providing sustained support beyond the initial period if NINDS expectations for continued outstanding performance and progress are met.

What is the practical takeaway for potential applicants?

This opportunity is a continuation gateway for a select group of investigators: current NINDS Javits Neuroscience Investigator Award (R37) recipients who are requesting up to three additional years of support as the second segment of their award.

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