Opportunity Information: Apply for RFA DK 22 037
The National Institutes of Health (NIH) is soliciting applications under Funding Opportunity Announcement RFA-DK-22-037 for an R25 Research Education Grant titled "Postbaccalaureate Research Education Program in Diabetes, Endocrinology and Metabolic Diseases (Independent Clinical Trial not Allowed)." The program is designed to help U.S.-based institutions build structured, mentored postbaccalaureate research experiences that prepare recent college graduates to successfully enter and complete rigorous, research-focused doctoral programs such as a Ph.D. or M.D./Ph.D. The central focus is workforce development in diabetes, endocrinology, and metabolic diseases (DDEMD), with an emphasis on supporting participants from diverse backgrounds and strengthening the pipeline into biomedical research careers tied to these scientific areas.
At its core, the FOA funds institutions to create a cohesive training environment that combines substantial, hands-on research immersion with formal coursework and skills development. The intent is not simply to place a participant in a lab, but to provide a well-designed program that helps bridge the gap between undergraduate education and doctoral-level biomedical research expectations. Programs are expected to offer extensive mentored research experiences specifically in DDEMD-related science, alongside structured learning activities that can build competencies needed for graduate school and long-term research success. Typical elements implied by the announcement include research training, professional development, and academic preparation that collectively improve readiness for competitive doctoral admissions and persistence in demanding research programs.
The long-term outcome NIH is aiming for is a stronger, more diverse group of scientists who go on to pursue careers focused on DDEMD-related research. Participants in these postbaccalaureate programs should be individuals whose trajectory is aimed toward research-intensive doctoral training, with the program serving as a launching point into that next stage. The FOA frames the program as a transition mechanism: recent graduates gain deeper research engagement, sharpen their scientific and professional skills, and become better positioned to enter and complete a doctoral degree in a biomedical field aligned with diabetes, endocrinology, and metabolic disease research.
Eligibility is a major defining feature of this opportunity. The applicant organization must be a domestic (U.S.) institution, and for the R25 described here, NIH specifies that applicants must be research-intensive, doctoral degree-granting institutions. In addition, the institution must demonstrate a substantial DDEMD research base, defined as at least $3 million in direct costs from peer-reviewed research projects in DDEMD science. This requirement signals that NIH expects awardees to already have robust, ongoing research activity and sufficient faculty expertise, infrastructure, and project diversity to support meaningful research placements for postbaccalaureate participants. Importantly, the research opportunities provided to participants must be in DDEMD science, reinforcing that the program is not meant to be a general biomedical postbac but one anchored in this specific scientific domain.
The FOA also lists a broad set of eligible applicant types in the source data, including various levels of government and a range of organizational categories (such as nonprofits, for-profits other than small businesses, small businesses, and institutions of higher education). It additionally highlights communities and institution types that are often central to diversity and capacity-building efforts, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), along with faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions. At the same time, the FOA is explicit that non-domestic entities are not eligible to apply: foreign organizations and foreign institutions cannot be applicants, non-U.S. components of U.S. organizations are not eligible, and foreign components as defined by NIH policy are not allowed.
Several administrative details further frame the opportunity. The award is a grant under a discretionary funding category, with the activity area aligned to food and nutrition and health, and it is associated with CFDA number 93.847. The opportunity lists an award ceiling of $375,000. The original closing date was October 25, 2023, and the FOA was created on February 27, 2023. The title includes "Independent Clinical Trial not Allowed," which indicates that the supported research education activities should not be built around running independent clinical trials under this award mechanism, consistent with NIH restrictions for certain training and education programs.
Overall, this FOA supports institutions in building a structured postbaccalaureate research education pathway in diabetes, endocrinology, and metabolic diseases, pairing strong mentored research experiences with intentional skills-building and coursework. NIH is prioritizing programs that can demonstrably prepare diverse recent graduates for the demands of research doctorates and, ultimately, grow the national pipeline of DDEMD-focused biomedical researchers, while requiring that awardee institutions have a substantial existing DDEMD research foundation and that all participant research experiences remain within DDEMD science.Apply for RFA DK 22 037
- The National Institutes of Health in the food and nutrition, health sector is offering a public funding opportunity titled "Postbaccalaureate Research Education Program in Diabetes, Endocrinology and Metabolic Diseases (R25 Independent Clinical Trial not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.847.
- This funding opportunity was created on 2023-02-27.
- Applicants must submit their applications by 2023-10-25. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $375,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQs)
What is this funding opportunity?
This opportunity is the NIH Funding Opportunity Announcement (FOA) RFA-DK-22-037 for an R25 Research Education Grant titled "Postbaccalaureate Research Education Program in Diabetes, Endocrinology and Metabolic Diseases (Independent Clinical Trial not Allowed)."
What is the purpose of the R25 postbaccalaureate research education program?
The purpose is to support U.S.-based institutions in building structured, mentored postbaccalaureate research experiences that help recent college graduates prepare to enter and complete rigorous, research-focused doctoral programs (such as a Ph.D. or M.D./Ph.D.), specifically in areas related to diabetes, endocrinology, and metabolic diseases (DDEMD).
Who is the program ultimately designed to benefit?
The program is intended to benefit recent college graduates who are aiming for research-intensive doctoral training and careers in biomedical research focused on DDEMD-related science. A major long-term goal is to strengthen and diversify the pipeline of scientists entering DDEMD research careers.
What scientific areas must the program focus on?
The central scientific focus must be diabetes, endocrinology, and metabolic diseases (DDEMD). The research opportunities provided to participants must be in DDEMD science, and the program is not intended to be a general biomedical postbaccalaureate program outside that domain.
What kinds of activities are expected in a funded program?
Based on the description provided, NIH expects a cohesive and intentionally designed training environment that includes substantial hands-on mentored research immersion in DDEMD-related science plus structured learning activities. This can include formal coursework, skills development, professional development, and academic preparation intended to improve readiness for competitive doctoral admissions and success in research-focused doctoral programs.
Is the goal simply to place participants into labs?
No. The FOA emphasizes that the intent is not simply to place a participant in a lab. Instead, the program should be structured and well-designed to bridge the gap between undergraduate education and doctoral-level biomedical research expectations.
What is the intended career and training trajectory for participants?
Participants are expected to be on a trajectory toward research-intensive doctoral training. The program is described as a transition mechanism that helps recent graduates deepen research engagement, sharpen scientific and professional skills, and become better positioned to enter and complete a doctoral degree aligned with DDEMD research.
Who can apply as the applicant organization?
The applicant organization must be a domestic (U.S.) institution. For this specific R25, NIH specifies that applicants must be research-intensive, doctoral degree-granting institutions.
Are foreign organizations eligible to apply?
No. The FOA is explicit that non-domestic entities are not eligible to apply. Foreign organizations and foreign institutions cannot be applicants, non-U.S. components of U.S. organizations are not eligible, and foreign components (as defined by NIH policy) are not allowed.
Does the applicant institution need to show an existing research base in DDEMD?
Yes. The institution must demonstrate a substantial DDEMD research base, defined as at least $3 million in direct costs from peer-reviewed research projects in DDEMD science. This indicates NIH expects robust ongoing DDEMD research activity and the faculty expertise and infrastructure to support meaningful mentored research placements.
What does "research-intensive, doctoral degree-granting" imply for eligibility?
As described in the opportunity summary, NIH requires that applicants for this R25 be institutions that grant doctoral degrees and have a strong research environment. This requirement is presented as a defining feature of eligibility for this FOA.
Are certain institution types specifically highlighted as eligible?
Yes. The FOA source data lists a broad set of eligible applicant types and also highlights institution types and communities often associated with diversity and capacity-building efforts, including HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.
How does the FOA address diversity and workforce development?
The FOA emphasizes workforce development in DDEMD and includes an emphasis on supporting participants from diverse backgrounds. The overall intent includes strengthening the pipeline into biomedical research careers tied to DDEMD.
What does "Independent Clinical Trial not Allowed" mean in the title?
It indicates that the supported research education activities under this award mechanism should not be built around running independent clinical trials under the grant, consistent with NIH restrictions for certain training and education programs.
What is the award ceiling listed for this opportunity?
The opportunity lists an award ceiling of $375,000.
What is the closing date and when was the FOA created?
The original closing date was October 25, 2023, and the FOA was created on February 27, 2023.
What is the funding mechanism and category?
The award is described as a grant under a discretionary funding category, using the R25 Research Education activity code.
Is there an associated CFDA number for this opportunity?
Yes. The opportunity is associated with CFDA number 93.847.
What activity area is this opportunity aligned with?
The opportunity is aligned with the activity area described as food and nutrition and health.
What is the overall outcome NIH is aiming for through this program?
The long-term outcome described is a stronger, more diverse group of scientists who go on to pursue careers focused on DDEMD-related research, supported by structured postbaccalaureate research education programs that prepare participants to enter and complete research-intensive doctoral training.
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